The drugs concerned should be illegal or used recreationally. The drugs must be real and not fantasy drugs.
Reference
Text, dialogue, lyrics, and/or images of illegal/recreational drugs would be considered references.
Use
The use/consumption of illegal/recreational drugs in any case would constitute use.
Encourages/Glamorizes
If characters gain advantage or achieve success after the use of illegal/recreational drugs, this would be considered encouragement/glamorization.